Fredette-Roman J, Smith DR, Omari SB, Sharp NP. (2026) Elevated mutation in haploid yeast driven by translesion synthesis. Under Revision. Preprint.
Katzenberger RJ, Sharp NP, Ganetzky B, Wassarman DA. (2026) Genetic variation in innate immune gene expression influences mortality after traumatic brain injury in Drosophila. G3: Genes|Genomes|Genetics jkag060. Link
Sohoni R, Schatz GG, Sharp NP. (2026). The effect of spontaneous mutations on CUP1 copy number and copper tolerance in Saccharomyces cerevisiae. Biology Letters (in press). Preprint.
Sandell L, Bazzicalupo AL, Otto SP, Sharp NP. (2026) Evolutionary responses to increased opportunity for sexual selection in yeast. BMC Ecology and Evolution 26, 16. Link.
Yun G, Liu R, Sharp NP. Quantitative genetics of trauma induced mortality in Drosophila melanogaster. Heredity. Link.
Melde RH, Daigle AT, Abraham JH, Sharp NP. (2026) Meiotic double strand breaks and spontaneous mutation in Drosophila melanogaster.G3: Genes|Genomes|Genetics jkag019. Link.
Bao K, Gupte R, Braker N, Sharp NP. (2025) Contrasting mutation patterns in haploid and diploid cells from two yeast species. Genetics iyaf282. Link.
Makovec ER, Kestell CC, Janke KK, Carter EJ, Ragsdale AP, Sharp NP. (2025) Fitness consequences of sex chromosome aneuploidy in Drosophila melanogaster. PLoS Genetics 21(6): e1011703. Link.
Thota K, Fredette-Roman JD, Sharp NP. (2025) Yeast mutation rates in alternative carbon sources reflect the influence of reactive oxygen species. microPublication Biology. 10.17912/micropub.biology.001429. Link.
Hose J, Zhang Q, Sharp NP, Gasch AP. (2024) On the rate of aneuploidy reversion in a wild yeast model. Genetics iyae196. Link.
Melde RH, Abraham JM, Ugolini MR, Castle MP, Fjalstad MM, Blumstein DM, Durski SJ, Sharp NP. (2024) Sex-specific viability effects of mutations in Drosophila melanogaster. Evolution 78:1844-1853. Link.
Bao K, Strayer BR, Braker NP, Chan AA, Sharp NP. (2024) Mutations in yeast are deleterious regardless of the degree of adaptation to the testing environment. Proceedings of the Royal Society B 291:20240064. Link.
Sharp NP, Smith DR, Driscoll G, Sun K, Vickerman CM, Martin SCT. (2023) Contribution of spontaneous mutations to quantitative and molecular variation at the highly repetitive rDNA locus in yeast. Genome Biology and Evolution 15:evad179. Link.
Melde RH, Bao K, Sharp NP (2022) Recent insights into the evolution of mutation rates in yeast. Current Opinion in Genetics and Development 76:101953. Link.
Bao K, Melde RH, Sharp NP (2022) Are mutations usually deleterious? A perspective on the fitness effects of mutation accumulation. Evolutionary Ecology 1:14. Link.
Sandell L, Sharp NP (2022) Fitness effects of mutations: An assessment of PROVEAN predictions using mutation accumulation data. Genome Biology and Evolution 14. Link.
Gerstein AC, Sharp NP (2021) The population genetics of ploidy change in unicellular fungi. FEMS Microbiology Reviews 45:fuab006. Link.
Sharp NP, Whitlock MC. (2019) No evidence of positive assortative mating for genetic quality in fruit flies. Proceedings of the Royal Society B 286: 20191474. Link.
Sharp NP, Sandell L, James CG, Otto SP. (2018) The genome-wide rate and spectrum of spontaneous mutations differ between haploid and diploid yeast. Proceedings of the National Academy of Sciences USA 115: E5046-5055. Link.
Sharp NP, Otto SP. (2018) Zeroing in on the rate of genome doubling. Current Biology 28: R306-R327. Link.
Sharp NP, Agrawal AF. (2018) An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components. Proceedings of the Royal Society B 285: 20181864. Link.
Gilbert KJ, Sharp NP, Angert AL, Conte GL, Draghi JA, Guillaume F, Hargreaves AL, Matthey-Doret R, Whitlock MC. (2017) Local adaptation interacts with expansion load during range expansion: Maladaptation reduces expansion load. American Naturalist 189: 368-380. Link
Sharp NP, Otto SP (2016) Evolution of sex: Using experimental genomics to select among competing theories. BioEssays 38: 751-757. Link.
Sharp NP, Agrawal AF (2016) Low genetic quality affects key dimensions of the mutational spectrum. PLoS Biology 14: e1002419. Link.
Sharp NP, Agrawal AF (2016) The decline in fitness with inbreeding: evidence for negative dominance-by-dominance epistasis in Drosophila melanogaster. Journal of Evolutionary Biology 29: 857-864. Link.
Sharp NP, Vincent CM (2015) The effect of parasites on sex differences in selection. Heredity 114: 367-372. Link.
Vincent CM, Sharp NP (2014) Sexual antagonism for resistance and tolerance to infection in Drosophila melanogaster. Proceedings of the Royal Society B. 281: 20140987. Link.
Wang AD, Sharp NP, Agrawal AF (2014) Sensitivity of mutational fitness effects to environment, genetic background, and adaptedness: a case study with Drosophila. Evolution 68: 840-853. Link.
Sharp NP, Agrawal AF (2013) Male-biased fitness effects of spontaneous mutations in Drosophila melanogaster. Evolution 67: 1189-1195. Link.
Clark SCA, Sharp NP, Rowe L, Agrawal AF (2012) Relative effectiveness of mating success and sperm competition offence at eliminating deleterious mutations in Drosophila melanogaster. PLoS ONE 7: e37351. Link.
Sharp NP, Agrawal AF (2012) Evidence for elevated mutation rates in low-quality genotypes. Proceedings of the National Academy of Sciences USA 109:6142-6146. Link.
Wang AD, Sharp NP, Spencer CC, Tedman-Aucoin K, Agrawal AF (2009) Selection, epistasis, and parent-of-origin effects on deleterious mutations across environments in Drosophila melanogaster. American Naturalist 174: 863-874. Link.
Sharp NP, Agrawal AF (2009) Sexual selection and the random union of gametes: Testing for a correlation in fitness between mates in Drosophila melanogaster. American Naturalist 174:613-622. Link.
Sharp NP, Agrawal AF (2008) Mating density and the strength of sexual selection against deleterious alleles in Drosophila melanogaster. Evolution 62:857-867. Link.